References

How the Woman Who Found a Leprosy Treatment Was Almost Lost to History. 2024. https://www.nationalgeographic.com/science/article/alice-ball-leprosy-hansens-disease-hawaiiwomens-history-science

Chaves LL, Patriota Y, Soares-Sobrinho JL Drug Delivery Systems on Leprosy Therapy: Moving Towards Eradication?.. Pharmaceutics. 2020; 12 https://doi.org/10.3390/pharmaceutics12121202

Collins SN The importance of storytelling in chemical education. Nat Chem. 2021; 13:1-2 https://doi.org/10.1038/s41557-020-00617-7

Ferry G A woman's place. Alice Ball: chemist who developed a treatment for leprosy. Lancet. 2023; 402 https//doi.org/10.1016/s0140-6736(23)01806-8

Lockwood DN, McIntosh A, Armstrong M Diagnosing and treating leprosy in a nonendemic setting in a national centre, London, United Kingdom 1995–2018. PLoS Negl Trop Dis. 2022; 16:(10) https://doi.org/10.1371/journal.pntd.0010799

Moberly T Cast in stone: university honours female pioneers. BMJ. 2020; 368 https://doi.org/10.1136/bmj.m246

Mushtaq S, Wermager P Alice Augusta Ball: The African American chemist who pioneered the first viable treatment for Hansen's Disease. Clin Dermatol. 2023; 41:147-158 https://doi.org/10.1016/j.clindermatol.2022.11.001

Alice Ball and leprosy

02 November 2024
Volume 6 · Issue 11

Abstract

In this month's article, George Winter discusses the forgotten story of Alice Ball, the chemist who pioneered a treatment for leprosy

As part of its 120th anniversary celebrations, in 2019 the London School of Hygiene and Tropical Medicine inscribed the names of Florence Nightingale (1820–1910), Marie Skłodowska-Curie (1867–1934), and Alice Augusta Ball (1892–1916) into the frieze around its Keppel Street building (Moberly, 2020). Many will be familiar with the first two names, but Brewster (2022) explains ‘How the Woman Who Found a Leprosy Treatment Was Almost Lost to History’.

Who was Alice Ball? Born in 1892 in Seattle, United States, into a family of African American photographers, Ball's family – she had three siblings – moved to Honolulu, Hawaii, in 1903; in 1905 they returned to Seattle; and in 1912 and 1914 Ball graduated from the University of Washington in pharmaceutical chemistry and pharmacy, respectively (Ferry, 2023).

In 1915 Ball graduated from the College of Hawaii (now the University of Hawaii) with an MSc, and for her thesis ‘she studied the chemical composition and active principle of the kava plant (Piper methysticum), which would later become the basis for her research on chaulmoogra oil’ (Mushtaq and Wermager, 2023).

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