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Opinion

Repurposed drugs

‘Klas et al (2023) consider how ethical issues acquired relevance during the COVID-19 pandemic, focusing on amantadine, a drug often used in neurological conditions’

Vaccine mandates

Almost a decade ago, Cunningham (2015) acknowledged vaccination as one of the major medical advances of modern times but added that ‘public health officials have become intoxicated by success and have...

A pill for everything?

Randomised controlled trials (RCTs) of patients with dementia or mild cognitive impairment demonstrated better cognitive scores after 6 to 12 months of exercise compared to sedentary controls. A RCT...

Navigating the art and science of appropriate prescribing

Prescribing, and in particular appropriate prescribing, is advocated as a mixture of science and art (Buetow et al, 1997)..

Metformin

Also known as French lilac, the herb Galega officinalis was used as a traditional medicine in medieval Europe, apparently helpful against worms, epilepsy and fever. In 1772 it was used to treat thirst...

Bacteriophages

The World Health Organization (WHO) has described antimicrobial resistance (AMR) as one of the top global public health and development threats, reporting that ‘bacterial AMR was directly responsible...

Continuous glucose monitors

‘The technological advances offered by continuous glucose monitors must be tested, evaluated, and demonstrated to be robust before being used outside clinical settings’ .

The role of nutrition in bipolar disorder

Loots et al (2021) note that psychiatric disorders comprise 13% of the total global disease burden, with non-adherence to medication ranging from 63–74% in patients with schizophrenia and some 50% in...

Cockroaches and antibiotic resistance

‘Given the relative rarity of cockroaches in Ireland …. at least one avenue of future research will involve tracing the evolutionary paths taken by Pseudocitrobacter and related micro-organisms’.

Hyperinsulinaemia

The idea of type 2 diabetes (T2D) being a progressive illness is almost redundant, with increasing evidence even confirming how T2D remission is possible. For example, Cucuzzella et al (2023: 146)...

Alzheimer's disease hypotheses

‘With Aβ accumulating in the brain through impaired clearance, not overproduction, Berger and Ede (2023) suggest that a possible explanation for this is reduced concentrations of insulin-degrading...

Probiotics and antibiotics

While promoting antibiotic stewardship, alternative antibiotic-free approaches to bacterial infections are being explored, including the use of probiotics, says George Winter

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