References
HALOPERIDOL
Abstract
In this column, Sharon Rees aims to refresh knowledge and interest in some of the commonly used drugs in a series of tweets. This month she is talking about #haloperidol
Dr Sharon Rees @reesprescribe
Day 1: #haloperidol was discovered mid-50s, as derived from chemical modification to opioids such as pethidine; it was found to have anti-psychotic effects, but no analgesia. Main uses include schizophrenia, manic episodes associated bipolar disorder, tic disorders such as tourette's, anti-emetic post-op/palliative
Dr Sharon Rees @reesprescribe
Day 1 (cont): #haloperidol can be used in children for adolescent schizophrenia, rapid treatment of aggression and tic syndrome. UK unlicensed use in palliative care
Dr Sharon Rees @reesprescribe
Day 2: Anti-psychotic adult dose range #haloperidol 2-10 mg/day in divided doses; some conditions such as aggression, tic disorder 0.5-5 mg. NOTE: lower doses elderly e.g start half adult dose and typically max 5 mg/day. Children dose range lower/variable depends on age and (sometimes) weight
Dr Sharon Rees @reesprescribe
Day 2 (cont): #haloperidol: i.m & s.c infusion for nausea and vomiting and delirium. Deep i.m depot inj (gluteal) in form of #haloperidol decanoate (oily) for long-term maintenance schizophrenia (where needed) dose 50-300 mg typically every 4 weeks
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