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Sharon Rees

Associate Professor Therapeutics and Prescribing, London South Bank University

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TIRZEPATIDE

Day 1: Following the diabetes & weight loss successes of GLP-1 agonists such as semaglutide, #tirzepatide is the 1st ‘dual’ incretin drug. Peptide engineering has been used to bring GLP-1 activity...

Drug Breakdown: Colchicine

With the help of Prescribing and Therapeutics Training Ltd and the Journal of Prescribing Practice, you can earn your 1-hour CPD certificate.

Domperidone

Day 1: After recognition that early antipsychotic drugs acting on dopamine pathways had an impact on vomiting, the search was on for an anti-emetic without extra pyramidal side-effects (EPS)....

Drug Breakdown: Fentanyl

Day 1: A synthetic opioid discovered circa 1960 (from phenylpiperidine) #fentanyl is x 50-100 more potent compared to morphine. Originally for anaesthetic i.v use; also now used for moderate-severe...

Drug breakdown: Bempedoic Acid

With the help of Prescribing and Therapeutics Training Ltd and the Journal of Prescribing Practice, you can earn your 1-hour CPD certificate.

Drug Breakdown: Isotretinoin

Day 1: A synthetic vitamin A derivative, #isotretinoin was discovered in the 1950s & originally used for skin cancer. Its effect on the cell cycle led to the discovery of efficacy for severe acne...

Drug Breakdown: Methylphenidate

Day 1: The mild CNS stimulant #methylphenidate was synthesised in the1940s & marketed as Ritalin by the 1950s, after recognition it improved concentration. Trialled for many conditions e.g chronic...

Drug Breakdown: Fosfomycin

Day 1: Originally derived from streptomyces bacteria (1960s), the main use for the synthetic oral form of #fosfomycin since the 1990s is for uncomplicated UTIs. Still available i.v for osteomyelitis,...

Drug Breakdown: Minoxidil

Day 1: A vasodilator derived from diallylmelamine in 1960s was found to have a BP lowering effect & #minoxidil was licensed 1970s. Long-term use revealed side-effect of hypertrichosis & trials for...

Drug Breakdown: Infliximab

Day 1: Monoclonal Antibody Drugs (MABs) were first generated in the 1970s and were first licensed in the 1980s for transplant rejection. The advancing technology in the 1990s led to improved B cell...

Book Review

This will be a useful and highly relevant resource for independent prescribers, whether they are clinicians considering a refresher or students/newly qualified NMPs who need a reference text. The...

Drug Breakdown: Carbimazole

With the help of Prescribing and Therapeutics Training Ltd and the Journal of Prescribing Practice, you can earn your 1-hour CPD certificate .

Drug Breakdown: Sitagliptin

Day 1: In the 1990s, growing insight into incretin roles in type 2 (T2DM) diabetes led to an interest in the breakdown of gut hormone GLP-1. DPP-4 was identified as the best peptidase target and a...

Drug Breakdown: Celecoxib

Day 1: The discovery of the COX-2 channel in the early 1990s led to two new NSAIDs designed and licensed with COX-2 selective action. The new drug target implied therapeutic and adverse drug effect...

Daptomycin

Day 1: #daptomycin was discovered in the late 1980s, when Streptomyces roseoporus bacteria was isolated from a Turkish soil sample. Adverse effects led to delays in clinical trials...

Why choose Journal of Prescribing Practice?

Journal of Prescribing Practice shares the latest clinical expertise and professional guidance for non-medical prescribers. Our goal is to provide the knowledge to help you prescribe more efficiently and effectively.

What's included

  • Evidence-based best practice

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  • Pharmacology information

  • Calculation skills

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