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Drug Breakdown

Daptomycin

Day 1: #daptomycin was discovered in the late 1980s, when Streptomyces roseoporus bacteria was isolated from a Turkish soil sample. Adverse effects led to delays in clinical trials...

Drug breakdown: Penthrox

With the help of Prescribing and Therapeutics Training Ltd and the Journal of Prescribing Practice, you can earn your 1-hour CPD certificate

Zopiclone

With the help of Prescribing and Therapeutics Training Ltd and the Journal of Prescribing Practice, you can earn your 1-hour CPD certificate.

Tacrolimus

Day 1: In the same class as ciclosporin A (superior to), #tacrolimus was found in Japan ©1984 from soil bacterium strep. tsukubaensis; the name is a combination of tsuku, macrolide and...

Drug breakdown: Indapamide

With the help of Prescribing and Therapeutics Training Ltd and the Journal of Prescribing Practice, you can earn your 1-hour CPD certificate.

Drug breakdown: caffeine

Day 1: Used for centuries as a stimulant, #caffeine was found via coffee bean analysis circa 1820, but is also found in the cocoa bean, guarana seeds, tea leaves etc; #caffeine can also be synthesised...

Quetiapine

Day 1: #quetiapine is a derivative of the 2nd generation atypical antipsychotic clozapine, with a superior side-effect profile. Developed in the 80s/90s, #quetiapine was approved for schizophrenia in...

Drug breakdown: allopurinol

Day 1: 1950s cancer drug investigations led to the discovery of 6-mercaptopurine; the kinetics revealed the breakdown role of xanthine oxidase (XO). Further tests showed that an analogue to naturally...

Drug breakdown: Nystatin

Day 1: Discovered via painstaking screening of soil samples in 1950 by Elizabeth Lee Hazen and Rachel Fuller Brown, #nystatin is a mixture of antifungal polyenes derived from the bacteria Streptomyces...

Drug breakdown: clopidogrel

Day 1: While searching for novel anti-inflammatory drugs in the 1980s, the prodrug #clopidogrel was discovered and launched worldwide in 1998 as an oral antiplatelet agent..

Drug breakdown: sertraline

Day 1: The investigation of tametraline psychoactive compounds led to the discovery of #sertraline in the USA in 1983; not licensed until 1991. Indicated for the treatment and prevention of major...

Drug breakdown: Alendronic acid

With the help of Prescribing and Therapeutics Training Ltd and the Journal of Prescribing Practice, you can earn your 1-hour CPD certificate.

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Journal of Prescribing Practice shares the latest clinical expertise and professional guidance for non-medical prescribers. Our goal is to provide the knowledge to help you prescribe more efficiently and effectively.

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