Naloxone hydrochloride for acute opioid events: answers

A 3-day-old preterm neonate is given morphine as post operative pain relief. They become bradycardic and apnoeic. They weigh 700 g. What dose of naloxone would you prescribe?

A 10-month-old child weighing 8.7 kg was administered fentanyl. They become unresponsive with respiratory depression. What dose of naloxone would you prescribe?

An 11 year old presents with reduced consciousness, respiratory depression and bradycardia following ingestion of heroin. Their weight is estimated to be 20 kg. What dose of naloxone would you prescribe?

An adult with a known opioid dependency has taken an accidental overdose of methadone. They had been given intranasal naloxone in the community but present with ongoing respiratory depression. They weigh 60 kg. What dose of naloxone would you prescribe?