References
New treatment hopes for Alzheimer's disease: A look at recent drug trials

Alzheimer's disease has been steadily on the rise in our ageing population and, alarmingly, those living with it have gone 20 years without new medicines (Gregory, 2023). However, recent advances in medicine have led to the first generation of possible treatments. Donanemab and lecanemab are two of the most recent medications showing good efficacy in trials. This article will explore these further.
Eli Lilly (2023) created donanemab, noting last year that 47% of participants taking the medication had no clinical progression at one year of the disease. However, the placebo group also had no progression at one year in 29% of participants. The Phase 3 trial for donanemab also met the primary endpoint and all secondary endpoints that measured cognitive and functional decline, finding that the treatment slowed clinical decline by 35%, and causing 40% less decline in the functional ability to carry out every day activities of daily living.
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