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Aysha Mendes

Freelance journalist, specialising in psychology and healthcare

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Opioid overdose and naloxone

“While naloxone is a prescription-only medicine (POM), exemptions have been developing over the years, owing to its potential to save lives” .

Assessing cardiac chest pain in prescribing practice

There are two broad stages of myocardial ischaemia: the first being stable angina; and the second being acute coronary syndromes, which include unstable angina and myocardial infarction (Paine, 2024).

Use of pharmacogenetics to guide cardiovascular drug prescribing

Clopidogrel is an antiplatelet therapy that is used to prevent myocardial infarction (MI) and stroke in individuals with acute coronary syndrome (ACS) (either managed medically or with PCI), those...

Prescribing indications, issues and concerns surrounding semaglutide

Several glucagon-like peptide receptor agonists used to manage blood glucose levels in people living with type 2 diabetes, have been in short supply globally. This includes glucagon-like peptide-1...

Reclassification and prescribing patterns of gabapentinoids

‘In April 2019, following a public consultation, as well as advice from the Advisory Council of the Misuse of Drugs, gabapentinoids were reclassified as Class C controlled substances and scheduled...

Parkinson's disease and the gut microbiome

A new study led by scientists in Japan analysed the microbiota of people living with Parkinson's, as well as those without, and noted that those with the disease have notably fewer bacterial genes...

Reinforcing the role of early glycaemic control in type 2 diabetes

The landmark UK prospective diabetes glucose-control studies carried out over 20 years, with data from 1977 to 1997 and published in 1998 were the first to show that complications from diabetes are...

Prescribing fluoroquinolone: from revolutionary to restricted

In the UK, there are currently five fluoroquinolones licensed for use, which can be taken orally, given intravenously or via inhalation. These include the most common, ciprofloxacin, which is used to...

Use of genomic medicine to uncover adverse effects related to direct oral anticoagulants

Cardiac arrhythmias represent a significant burden, affecting morbidity and mortality (Gheorghe-Andrei et al, 2018). Atrial fibrillation (AF) is the most common arrhythmia, and prevalence not only...

New treatment hopes for Alzheimer's disease: A look at recent drug trials

Eli Lilly (2023) created donanemab, noting last year that 47% of participants taking the medication had no clinical progression at one year of the disease. However, the placebo group also had no...

The importance of communication as a prescriber

‘Prescribers should become aware of the characteristics of the setting in which they work, and be conscious of how this may influence communication and patient interactions’.

Evolution of the use of quetiapine

Duncan et al (2016) published a study in the BMJ Open, which evaluated trends in the prescribing of quetiapine to adults in the Canadian province of Alberta between 2008 and 2013.

Preventing urinary tract infection and supporting patient catheterisation for mental health

A tool has been developed that requires a health professional to carry out the assessment (Lauridsen et al, 2022). A UTI risk factor model was used as the basis to inform the content included in the...

The hidden risks of fluoroquinolones

A study published late last year in the British Medical Journal (Wang et al, 2022) evaluated the association between the initiation of fluoroquinolones and admissions to hospitals or emergency...

Machine learning for precision treatment

Sotomi et al (2023) examine the use of machine learning to identify cohorts of a population that may benefit from specific medications. The team had previously established a machine learning-based...

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