References
Effective pharmaceutical management of Acute Otitis Externa: guidance and prescribing considerations

Abstract
Acute Otitis Externa is a common condition observed by physicians, particularly in primary care. The condition usually occurs due to bacterial infection, so antibiotic therapy is frequently indicated. Oral antibiotics are rarely necessary but are still being prescribed, despite a wide range of available topical preparations. Choosing a topical preparation can sometimes be challenging for prescribers, however, consideration of a range of different factors is necessary. This article provides a review of the currently recommended prescribing practice and outlines key topical antibiotic ear preparations available in the UK for treatment of Acute Otitis Externa. As no one topical ear preparation is more effective than another, a consideration of the benefits and risks of each treatment is needed to enable therapeutic resolution of Acute Otitis Externa. Furthermore, patient compliance should be adequately considered to increase the likelihood of patient adherence to treatment.
Acute otitis externa (AOE), also known as swimmer's ear, is defined by widespread inflammation of the external auditory canal and is considered acute if it lasts three weeks or less (National Institute for Health and Care Excellence (NICE), 2018). The symptoms of AOE range from mild to severe and include ottorhoea, erythema, pain and oedema. One third of patients may also suffer from some form of hearing loss (Hui et al, 2013).
The condition usually occurs due to bacterial infection, and the microbiology surrounding AOE is widely established. The principle pathogens of the condition are Pseudomonas aeruginosa and Staphylococcus aureus, and the infection often occurs in a polymicrobial setting (NICE, 2018). Fungal involvement is uncommon in primary AOE, but is more common in cases of chronic otitis externa or when AOE has previously been treated with topical antibiotics (Rosenfield et al, 2014).
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