This section will delve into the specific changes that occur in the pharmacokinetic processes – absorption, distribution, metabolism, and excretion – as people age. Each subsection will discuss the...
Infected people shed hepatitis A virus in their faeces and are most infectious 1–2 weeks before they get any clinical signs and symptoms, such as jaundice or raised liver enzymes (when virus...
The appropriate management of asthma and COPD remains challenging despite the availability of effective treatments. It must be acknowledged that merely prescribing the right medication is insufficient...
Risks of transplant include rejection, primary graft dysfunction, immunosuppression side effects such as infection, weight gain, hypertension, diabetes, osteoporosis and cardiac allograft vasculopathy...
Descriptive statistics were used to describe frequency of clinical score documentation, symptom documentation and antibiotic prescription rates. The initial plan to ascertain non-inferiority...
‘Rational use of medicines requires that patients receive medications appropriate to their clinical needs, in doses that meet their own individual requirements, for an adequate period of time, and...
Parkinsonism is an umbrella term for conditions that present with symptoms typically seen in Parkinson's disease (which accounts for around 85% of cases of parkinsonism) (McFarland and Hess, 2017;...
Nisha, a 55-year-old female housekeeper, was referred for physiotherapy pelvic health review with a 2-year history of daily episodes of urinary incontinence when coughing, sneezing and when at work,...
The primary aim of this review was to establish how to implement sustainable inhaler changes without compromising patient care and disease control in the primary care setting. This includes a review...
The purpose of the spacer device is to act as an intermediary chamber into which a pressurised metered dose inhaler (pMDI) can discharge the drug. This slows down the drug, which is propelled at force...
MART as a regimen works because it allows for automatic self-titration. By its very nature, the patient will take more ICS doses when they are symptomatic and default to baseline (preventer therapy...
CYP450 enzymes increase clearance of contraceptive hormones, making them less effective. This includes all combined hormonal contraceptives, all progestogen-only pills (POP), the etonogestrel implant...
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