References

Joint Formularies Committee. DIGOXIN | Drug | BNF content published by NICE. https://bnf.nice.org.uk/drug/digoxin.html#indicationsAndDoses (accessed 5 January 2022)

PubChem. Digoxin | C41H64O14 - PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Digoxin#section=Solubility (accessed 5 January 2022)

ToxBase. Digitalis purpurea (Foxglove). Toxbase. https://www.toxbase.org/poisons-index-a-z/f-products/foxglove/ (accessed 2 January 2022)

Poisoning with homemade remedies: answers

02 February 2022
Volume 4 · Issue 2

Given that dried leaves may contain up to 0.225%w/w digoxin (ToxBase, no date) calculate the theoretical maximum amount of digoxin in the dried leaves. N.B. 1 dram = 1.77 g.

What will the final concentration of the solution be, in %w/v, after it has been boiled down to the final volume of two quarts, assuming the extraction yields 90% efficiency?

Based on how much she has been taking for each dose, what is her total daily dose of digoxin, compare this to the usual starting dose for digoxin (Joint Formularies Committee, no date).

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