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Stephen Bennett

Advanced Specialist Paediatric Pharmacist (Cardiology/Critical Care/ECMO) Leicester Royal Infirmary and De Montfort University

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Sildenafil treatment for pulmonary hypertension: IV initiation and conversion to oral

What will the loading dose, in mg, be for this patient? Load dose = 400 micrograms/kg = 0.4mg/kg x 2.7kg = 1.08 mg, to be given over 3 hours .

Administration and conversion of paediatric sedation using benzodiazepines

If the patient has a syringe set up which contains 45 mg/50 ml of midazolam and is running at 1.5 ml/hour, what is the dose the patient is receiving in microgram/kg/hour? .

Administration and conversion of paediatric sedation using benzodiazepines: answers

What rate of infusion will meet the threshold for converting for this patient? .

Surface area-based dosing of caspofungin in children

What is the body surface area for this child?

Surface area-based dosing of caspofungin in children: Answers

What is the body surface area for this child? 9.98 kg × 77.7 cm = 775.446 kg/cm 775.446/3600 = 0.2154 0.2154 = 0.464   m 2 In practice it is also...

Excipient induced laxative thresholds

Based on the information above, what is the minimum expected amount of sorbitol (in g) for an adult that could produce a laxative effect?

Excipient induced laxative thresholds: answers

Based on the information above, what is the minimum expected amount of sorbitol (in g) for an adult that could produce a laxative effect?

Maintaining a patent ductus arteriosus with prostaglandins

The following scenario considers the case of a 2 kg neonate with critical pulmonary stenosis that requires a continuous intravenous infusion of prostaglandin E2 to prevent her duct from closing. The...

Maintaining a patent ductus arteriosus with prostaglandins: answers

What is the concentration of the syringe (in ng/ml) to be used for this child?

Management of obesity

Consider a patient who has approached you for a prescription for orlistat who is keen to lose weight and has the following anthropometrics: male, 44 years old, 185 cm tall, 113 kg. He has no other...

Managing obesity: answers

Does this patient meet the NICE criteria for commencing orlistat (NICE, 2014)? Calculate his BMI using the formula:

Dosing of mesna to avoid urothelial toxicity from cyclophosphamide infusion

Given that they weigh 7 stone 13lb and are 5′4′′ tall, use the Mosteller (1987) formula (Figure 1) for body surface area to calculate the dose determining body surface area in m2. .

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