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Stephen Bennett

Advanced Specialist Paediatric Pharmacist (Cardiology/Critical Care/ECMO) Glenfield Hospital and De Montfort University

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Surface area-based dosing of caspofungin in children

What is the body surface area for this child?

Surface area-based dosing of caspofungin in children: Answers

What is the body surface area for this child? 9.98 kg × 77.7 cm = 775.446 kg/cm 775.446/3600 = 0.2154 0.2154 = 0.464   m 2 In practice it is also...

Excipient induced laxative thresholds

Based on the information above, what is the minimum expected amount of sorbitol (in g) for an adult that could produce a laxative effect?

Excipient induced laxative thresholds: answers

Based on the information above, what is the minimum expected amount of sorbitol (in g) for an adult that could produce a laxative effect?

Maintaining a patent ductus arteriosus with prostaglandins

The following scenario considers the case of a 2 kg neonate with critical pulmonary stenosis that requires a continuous intravenous infusion of prostaglandin E2 to prevent her duct from closing. The...

Maintaining a patent ductus arteriosus with prostaglandins: answers

What is the concentration of the syringe (in ng/ml) to be used for this child?

Management of obesity

Consider a patient who has approached you for a prescription for orlistat who is keen to lose weight and has the following anthropometrics: male, 44 years old, 185 cm tall, 113 kg. He has no other...

Managing obesity: answers

Does this patient meet the NICE criteria for commencing orlistat (NICE, 2014)? Calculate his BMI using the formula:

Dosing of mesna to avoid urothelial toxicity from cyclophosphamide infusion

Given that they weigh 7 stone 13lb and are 5′4′′ tall, use the Mosteller (1987) formula (Figure 1) for body surface area to calculate the dose determining body surface area in m2. .

Dosing of mesna to avoid urothelial toxicity from cyclophosphamide infusion: answers

Given that they weigh 7 stone 13lb and are 5′4′′ tall, use the Mosteller (1987) formula (Figure 1) for body surface area to calculate the dose determining body surface area in m2. .

Calculating osmolarities of peripheral infusions to avoid thrombophlebitis

Show that 10% w/v glucose will be unable to provide the target glucose infusion rate with this limited amount of fluid available. .

Calculating osmolarities of peripheral infusions to avoid thrombophlebitis: answers

Show that 10% w/v glucose will be unable to provide the target glucose infusion rate with this limited amount of fluid available. .

Poisoning with homemade remedies

Given that dried leaves may contain up to 0.225%w/w digoxin (ToxBase, no date) calculate the theoretical maximum amount of digoxin in the dried leaves. N.B. 1 dram = 1.77g. .

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