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Prescribing for persistent cancer pain: focus on chemotherapy-induced peripheral neuropathy

02 April 2020
Volume 2 · Issue 4

Abstract

Chemotherapy-Induced peripheral neuropathy is rapidly becoming a growing problem faced by healthcare processionals and individuals living with and beyond cancer. The incidence of cancer diagnoses is increasing and, as a result, so is the incidence of individuals living with the consequences of cancer treatment. Chemotherapy-induced peripheral neuropathy is a complex symptom, and its incidence and impact on quality of life varies across treatment modalities. This complexity continues into its assessment and management, and healthcare professionals require more support and guidance when presented with this pain state. This article will explore the current literature surrounding assessment methods and management strategies that will enable prescribers to make informed decision when encountering chemotherapy-induced peripheral neuropathy.

The incidence of a cancer diagnosis within the UK is rising, with an estimated increase of 40% by 2035 (Cancer Research, 2019). However, as treatment modalities and screening become more sophisticated there are more individuals living longer with and as a result of a cancer diagnosis (Cancer Research, 2019).

As the incidence of cancer increases, so does the incidence of individuals living with pain as a direct result of cancer treatment. It is estimated that 66% of individuals with advanced disease and 39% who have completed curative treatment will report pain (Van den Beuken-van Everdingen et al, 2016). Persistent cancer pain is complex and multifactorial, and can have a detrimental impact on patients' quality of life, as it affects not only physical domains but also has a significant impact on psychosocial domains (Sun et al, 2008). Despite the complex nature of persistent cancer pain, it remains poorly understood and managed (Sun et al, 2008).

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