References
Managing smoking cessation in primary care

Abstract
Smoking remains a significant preventable cause of serious chronic diseases. Smokers should be advised about quitting at every opportunity, using very brief advice as a quick and reliable method to instigate empathetic support and understanding, which encourages smokers to consider quitting. Nicotine replacement therapy, especially combining a long-release and short-release formulae, should be the first step in the use of pharmaceutical aids. Ideally, heavily dependent smokers should also be prescribed varenicline, but this is currently unavailable in the UK. An alternative is bupropion, which should be a consideration. However, it is less effective, with more side effects. Electronic cigarettes have been recommended as a suitable quitting aid, and also for harm reduction in those who are not yet ready to stop smoking.
The UK has experienced a dramatic reduction in smoking prevalence of about 75% over the last 60 years (Royal College of Physicians (RCP), 2021). However, if the recent, rather slow, rate of reduction continues, it is predicted that the UK will still be a long way from eradicating smoking by 2050, a plan that was advocated in the 1962 UK White Paper ‘Smoking and Health’ (RCP, 1962). Despite the reduction in smoking prevalence in the UK, smoking remains the most important avoidable cause of premature death and disability in the UK, and the biggest preventable cause of cancer. The latest figures show that 14.1% of people aged 18 years or older smoke cigarettes, which equates to around 6.9 million individuals (Cancer Research UK, 2022). Worryingly, a new study found that the number of 18–34-year-olds in England who smoke, increased by 25% during the first lockdown, meaning that there are over 652 000 more young adults who smoke than before the pandemic (Jackson et al, 2022).
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