References
Delayed prescribing of antibiotics for self-limiting respiratory tract infections in an urgent care out-of-hours setting

Abstract
Long-term overuse of antibiotics and inappropriate prescribing has led to widespread development of antimicrobial resistance. The Department of Health and Social Care recently published a five-year national action plan to reduce antimicrobial resistance, with the aim of reducing inappropriate antibiotic prescribing. This is mirrored in the NHS Long Term Plan, which aims to reduce unintentional exposure through a combination of antibiotic stewardship and leadership at all levels. An acute respiratory tract infection is one of the most common presentations in primary care, with 16.7% of all prescriptions issued attributed to it. Therefore, out-of-hours prescribers contribute significantly to general antibiotic consumption. This article analyses the practice of delayed prescribing of antibiotics for the treatment of self-limiting respiratory tract infections in an out-of-hours service. The advantages and disadvantages associated with delayed prescribing, to safely treat patients whilst facilitating the reduction of antimicrobial resistance, are discussed. In addition, recommendations for future practice are offered. This article also focuses on the development of an advanced nurse practitioner, reflecting on the four pillars of advanced practice, which underpin advanced clinical practice and associated competencies.
Continued inappropriate prescribing alongside the overuse of antibiotics has caused the widespread development of antimicrobial resistance (AMR) (Public Health England (PHE), 2015). Global deaths due to infections as a result of AMR are estimated at 700 000 each year, and this figure is predicted to rise (World Health Organization, 2018). The Department of Health and Social Care (DHSC) recently published a five-year national action plan, aiming to reduce antibiotic prescriptions and improve prescribing practice (DHSC, 2019). The NHS Long Term Plan, also aims to optimise antibiotic use and reduce unintentional exposure, through a combination of antibiotic stewardship and leadership at all levels (NHS, 2019). This is particularly pertinent when practising as an advanced nurse practitioner (ANP).
Acute respiratory tract infection (RTI) is one of the most common presentations in primary care (National Institute for Health Care Excellence (NICE), 2008). RTIs include the common cold, sore throat, otitis media, cough, tonsillitis, pharyngitis, rhinosinusitis, and bronchitis (NICE, 2008). Out-of-hours (OOH) is an integral service to primary care; 16.7% of prescriptions are issued for RTI, therefore OOH prescribers contribute significantly to general antibiotic consumption (Lindberg et al, 2017). Patients with viral RTIs rarely need antibiotics, as they are generally self-limiting, unless there is an underlying comorbidity (Huang et al, 2013; NICE, 2008; PHE, 2019). Prescribing antibiotics unnecessarily drains NHS resources and creates the risk of serious outcomes for patient health, including associated side effects and AMR (Costelloe et al, 2010). Furthermore, inappropriate use of antibiotics and beliefs about the effectiveness of antibiotics encourage patients to re-consult, thereby reducing the probability of self-management (Williamson et al, 2006). PHE recently published research indicating that 20% of antibiotic prescribing in primary care is inappropriate (Davies, 2018). An immediate 10% reduction of prescribing is required to meet the government target, which aims to reduce antibiotic prescriptions by 50% by the end of 2020 (DHSC, 2019).
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