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Updates

The National Institute for Health and Care Excellence (NICE) has recommended a weight loss drug to be made available in specialist NHS services. The drug, semaglutide, has shown promising results in...

Drug Breakdown: Infliximab

Day 1: Monoclonal Antibody Drugs (MABs) were first generated in the 1970s and were first licensed in the 1980s for transplant rejection. The advancing technology in the 1990s led to improved B cell...

Machine learning for precision treatment

Sotomi et al (2023) examine the use of machine learning to identify cohorts of a population that may benefit from specific medications. The team had previously established a machine learning-based...

Examining prescribing in children and adolescents

This cohort study, published in The Lancet Psychiatry journal, aimed to identify trends in antipsychotic drug prescribing to children and adolescents in England (Radojčić et al, 2023). This was driven...

The risks and rewards of semaglutide in obesity treatment

The connection between the pancreas, the gut and incretins – hormones released into the blood by the intestine in response to food – was established in the early twentieth century (Knudsen and Lau,...

What is bronchitis and how is it managed?

One of the primary symptoms of acute bronchitis is a cough, which can be productive or unproductive. Other symptoms or clinical signs that may suggest lower respiratory tract infection and no...

Managing smoking cessation in primary care

The revised NICE (2021) guidelines (NG209): Tobacco: preventing uptake, promoting quitting and treating dependence, recommended greater flexibility and clearer guidance in the use of nicotine...

Avoiding and managing the side effects of type 2 diabetes treatments

When considering a treatment to improve glycaemic control, it is important to involve the individual in the decision-making process and to consider their specific circumstances and potential...

Book Review

This will be a useful and highly relevant resource for independent prescribers, whether they are clinicians considering a refresher or students/newly qualified NMPs who need a reference text. The...

Prescribing during pregnancy

This article was published in BMC Medicine, used a retrospective cohort study approach to examine data between 2000 and 2019 (Subramanian et al, 2023). The author's main driver to conduct this...

The importance of adhering to regulations in healthcare: lessons from the COVID-19 pandemic and historical incidents

When it comes to safety in healthcare, rules, regulations and guidance are essential to help secure protection for patients and healthcare workers. For example, the Health and Safety Executive (2023)...

Are opioids being over-prescribed in gynaecology surgery?

Data were retrospectively collected from patient cases that were admitted to the gynaecology ward following gynaecology surgery at a tertiary care hospital in the UK, between 1 July 2019 and 30...

How to complete a safe and effective contraceptive consultation

The FSRH have produced a service standard for record keeping in sexual and reproductive healthcare consultations (FSRH, 2019a). It recommends clear documentation of clinical history, assessment,...

Iron supplementation for iron-deficiency anaemia

Evidence to date suggests that the liquid form of iron supplementation has comparable efficacy to the tablet formulation, but with significantly lower gastrointestinal side effects. The evidence...

Treatment of adjustment disorders in mental health crisis care: a reflective case study

John (a pseudonym used to protect his identity) was a 54 year-old man who was referred to the mental health crisis resolution team by his GP after attempting suicide. There had been a 1-month history...

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