References

Johnson M, Cosentino D, Fuehrlein B A detox dilemma beyond benzodiazepines; clonidine's quandary in alcohol withdrawal management. Am J Addict. 2025; 34:(1)101-103 https://doi.org/10.1111/ajad.13640

O'Regan A, Lee JR, McDermott CL, Cohen HJ, Merlin JS, Marais AD, Winn AN, Meghani SH, Check DK Opioids and benzodiazepines in oncology: Perspectives on coprescribing and mitigating risks. J Geriatr Oncol. 2024; 16:(2) https://doi.org/10.1016/j.jgo.2024.102172

Pöytäkangas T, Basnyat P, Rainesalo S, Peltola J, Saarinen JT Use of benzodiazepines in patients with status epilepticus requiring second-line antiseizure medication treatment. Epilepsy Res. 2025; 210 https://doi.org/10.1016/j.eplepsyres.2025.107507

Benzodiazepine prescribing

02 March 2025
Volume 7 · Issue 3

Abstract

Deborah Robertson provides an overview of recently published articles that may be of interest to non-medical prescribers. Should you wish to look at any of the papers in more detail, a full reference is provided

Last month, the research round-up provided you with an overview of three varied articles on the topic of opioid stewardship. This month, we will review three articles concerned with prescribing benzodiazepines.

The first article looks at the co-prescribing of opioids and benzodiazepines in oncology care. The second article reviews the use of benzodiazepines in status epilepticus. Finally, our third article deals with benzodiazepine use versus clonidine in alcohol withdrawal management.

This article, published in the Journal of Geriatric Oncology, sought to understand the practices of cancer care providers around the prescription of opioids and benzodiazepines when co-prescribed in cancer care, and to elucidate and mitigate potential harms.

The research aimed to understand the extent of this common co-prescribing pairing using outpatient settings in two large academic medical centres located on the eastern border of the United States. These centres provided oncological and palliative care management of pain and other symptoms. This qualitative study, using semi-structured interviews, sought attitudes on current prescribing practices for opioids and benzodiazepines and included factors affecting clinical decision-making and risk mitigation between March and September 2023. Interviewees included medical doctors and advanced practice providers. In total, 20 providers were recruited with an even split between oncology and palliative care settings.

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