Pharmacotherapeutics of aprepitant and pregabalin in neuropathic pain and refractory pruritus in a patient diagnosed with a cutaneous T-cell lymphoma

An audit of the prescription and supply of medicines by podiatric surgery teams in the UK

The Podiatric Audit in Surgery and Clinical Outcome Measure (PASCOM) is organised into an invasive domain (nail surgery, injection therapies and podiatric surgery) and a non-invasive domain (high...

Maintenance niraparib therapy for patients with relapsed platinum sensitive ovarian cancer: experience at a south coast network

PARP inhibitors have recently entered the treatment pathway for gynaecological cancers; primarily ovarian, fallopian tube and peritoneal cancers (The National Institute of Health and Care Excellence...

Ozanimod for relapsing remitting multiple sclerosis and how Brexit changed the journey

In 1997, Beta-interferon 1a (Avonnex) was licenced in the European Union (EU) for RRMS to reduce the impact and disease process of MS. Today there is a mixture of tablets, injections and infusions...

Acalabrutinib in the management of chronic lymphocytic leukaemia

Many patients with CLL require surveillance only and have a normal life expectancy, with the majority of patients monitored with a watch and wait approach until the balance of risk and benefits...

Nurse-led early evaluation following corticosteroid prescription in patients with inflammatory bowel disease

A system for evaluation of patients starting corticosteroids was established at the start of March 2020 by the IBD CNS team at the Dudley Group NHS Foundation Trust. This followed a route-cause...

Understanding the pharmacology of heart failure

HF is defined by the American College of Cardiology/American Heart Association (ACC/AHA) as a complex clinical syndrome that occurs from any structural or functional impairment of ventricular filling...

Nutrition and oncology: best practice and the development of a traffic light system

Multidisciplinary working is vital to proactively manage the nutritional care of oncology patients, whether this is via oral nutritional support or prophylactic/reactive enteral feeding..

Pharmacokinetics in paramedic prescribing

Absorption is the process a drug undergoes to enter the circulation. The most common route is the oral route, where drugs are ingested orally, and then absorbed from the gastrointestinal tract into...

Meeting demand for opioid dependency in an Inner London borough

The Benzodiazepine and Opiate Withdrawal Service (BOWS) service is a recently developed service to treat patients for dependency on codeine based drugs prescribed or used illicitly, benzodiazepines...

Management of COPD exacerbations: pharmacotherapeutics of medications

COPD is described as a preventable and treatable group of lung conditions characterised by airflow obstruction that is not fully reversible (Global Initiative for Chronic Obstructive Lung Disease...