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Calculation Skills

Sildenafil treatment for pulmonary hypertension: IV initiation and conversion to oral

What will the loading dose, in mg, be for this patient? Load dose = 400 micrograms/kg = 0.4mg/kg x 2.7kg = 1.08 mg, to be given over 3 hours .

World Health Organization fungal priority pathogens list

The polyenes are the oldest family of antifungal drugs and were introduced in the late 1950s..

World Health Organization fungal priority pathogens list: answers

Adult, weighing 65 kg with aspergillosis is prescribed IV amphotericin B by intravenous infusion. The BNF recommends 3 mg/kg once daily with a maximum dose of 5 mg/kg per day. What minimum and maximum...

Calculating the half-life of medications

Half-life is the time taken for the concentration of drug in the plasma to fall by half. It is important for prescribers to have knowledge of the concept of half-life, in order to understand the...

Administration and conversion of paediatric sedation using benzodiazepines

If the patient has a syringe set up which contains 45 mg/50 ml of midazolam and is running at 1.5 ml/hour, what is the dose the patient is receiving in microgram/kg/hour? .

Administration and conversion of paediatric sedation using benzodiazepines: answers

What rate of infusion will meet the threshold for converting for this patient? .

Surface area-based dosing of caspofungin in children

What is the body surface area for this child?

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