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Calculation Skills

Calculating the half-life of medications

Half-life is the time taken for the concentration of drug in the plasma to fall by half. It is important for prescribers to have knowledge of the concept of half-life, in order to understand the...

Administration and conversion of paediatric sedation using benzodiazepines

If the patient has a syringe set up which contains 45 mg/50 ml of midazolam and is running at 1.5 ml/hour, what is the dose the patient is receiving in microgram/kg/hour? .

Administration and conversion of paediatric sedation using benzodiazepines: answers

What rate of infusion will meet the threshold for converting for this patient? .

Surface area-based dosing of caspofungin in children

What is the body surface area for this child?

Surface area-based dosing of caspofungin in children: Answers

What is the body surface area for this child? 9.98 kg × 77.7 cm = 775.446 kg/cm 775.446/3600 = 0.2154 0.2154 = 0.464   m 2 In practice it is also...

Antimicrobial treatment of neonatal meningitis

Baby A, weight 3500 g and 4 days of age, is clinically unwell with suspected neonatal meningitis. .

Antimicrobial treatment of neonatal meningitis: answers

Baby A, weight 3500 g and 4 days of age, is clinically unwell with suspected neonatal meningitis .

Excipient induced laxative thresholds

Based on the information above, what is the minimum expected amount of sorbitol (in g) for an adult that could produce a laxative effect?

Excipient induced laxative thresholds: answers

Based on the information above, what is the minimum expected amount of sorbitol (in g) for an adult that could produce a laxative effect?

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