Titrating medicines to treat neuropathic pain

02 June 2019
Volume 1 · Issue 6

Several oral medicines that are used in the management of neuropathic pain require dose titration. This month's calculation skills ask you to calculate the total quantities of medicines that would need to be prescribed for these scenarios:

Sean wants to prescribe pregabalin for his patient with neuropathic pain. He wants to start with 75 mg twice daily for 7 days, then increase the dose to 150 mg twice daily. He will be reviewing his patient after 4 weeks.

How many 75 mg capsules should be prescribed for 4 weeks?

Gill wants to prescribe gabapentin for her patient, a 42-year-old male. She checks the Summary of Product Characteristics and finds the following dosage advice:

For all indications, a titration scheme for the initiation of therapy is described in Table 1, which is recommended for adults and adolescents aged 12 years and above.

How many gabapentin 300 mg capsules are required for a prescription that will last 2 weeks (until she reviews her patient)?

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