It is estimated that £300 million is wasted on medicines in the UK each year. The causes of waste vary, from inefficient prescribing and stockpiling to patient recovery and non-adherence. Pharmaceutical waste can occur at any stage from the point of prescribing to the taking/not taking of medicines by the patient, and can occur through failures in existing processes or patient behaviours. The prescriber, dispenser and patient all play a part in the creation of waste. Repeat prescribing can contribute to medicine waste in a number of ways (NHS England, 2023):
- Items prescribed/dispensed, but not required by patients
- Items dispensed without being requested by the patient
- Patients over-ordering to create a stockpile of medication (often this applies to ‘when required’ medication)
- Patient concerns over medicine shortages (having ‘plenty of medicines as a stand-by’)
- Patient concerns over effects of non-adherence: ‘Always ask for everything on the slip … don't want to run out, easier to say everything, don't want doctor to think I'm not using them properly by not re-ordering’.

In primary care, a review of high-cost drug prescribing can reveal areas of waste, not to mention opportunities to address patient safety issues and improve patient care.
Case scenario
The following scenario shows the prescribing cost of three medicines in general practice over a 1-month period. Work out the monthly cost savings after reviewing each prescription.
Case scenario | ||||||||
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Drug | Directions | Quantity prescribed | Cost for 1-month supply | Problem | Outcome after review | Directions after review | Quantity after review | Monthly cost saving |
A | One to be taken three times a day | 84 | £1428 | Dose on discharge letter stated ‘One to be taken three times a week’ | Prescription was reviewed and updated | One to be taken three times a week | 12 | ? |
B | One to be taken daily | 28 | £987 | Red traffic light medicine for prescribing only by hospital specialist | Prescribing of the medicine transferred back to specialist | N/A | 0 | ? |
C | One to be taken daily | 2 x 84 | 2 x £282 | Patient was over-ordering; the prescription was issued twice in the last month | Prescribed quantity was reduced to a 28-day supply | One to be taken daily | 28 | ? |