Drug Breakdown: Celecoxib

Day 1: The discovery of the COX-2 channel in the early 1990s led to two new NSAIDs designed and licensed with COX-2 selective action. The new drug target implied therapeutic and adverse drug effect...

Updates

The batches shown in Table 1 of Targocid 200 mg powder for injection/infusion or oral solution are being recalled immediately by Sanofi UK. This is due to out of specification results for bacterial...

The question of social prescribing

A new review, published in the BMJ Open (Kiely et al, 2022), found that there is no consistent evidence that social prescribing improves social support or physical function, or reduced the use of...

Daptomycin

Day 1: #daptomycin was discovered in the late 1980s, when Streptomyces roseoporus bacteria was isolated from a Turkish soil sample. Adverse effects led to delays in clinical trials...

Smoking cessation support and treatment services

In 2021, the British Thoracic Society (BTS, 2022) carried out a national audit of the management of tobacco dependency in acute care trusts, following previous audits in 2019 and 2016. The audit...

Serotonin and depression

George Winter discusses the role of serotonin when deciding how to treat depression and how new papers are now disputing the role in plays and whether antidepressants are even the correct treatment...

Polypharmacy and the older adult

This review of the literature published in the Journal of Geriatric Oncology aimed to elucidate the scale of the issue in a population of older adult patients with cancer and to discuss the...

Non-medical midwifery prescribing of an antiemetic for a glucose tolerance test: a case study

The Calgary-Cambridge model was chosen to assess this case study because it was the most structured, practical, patient-centred model and it allows a way to close the session when compared to the...

The influence of non-medical prescribers on antimicrobial stewardship: a national evaluation of the impact of the COVID-19 pandemic on the prescribing of antibiotics by non-medical prescribers in England in 2020 (part 2)

Prescribing data for antibiotics prescribed by NMPs in primary care and dispensed in the community was obtained from NHS Business Services Authority and the regulating bodies for the professions with...

How to relate progestogen-only pill guidance to clinical practice

There will soon be four different POPs available in the UK. Most clinicians will be familiar with the desogestrel (DSG) 75 µg POP and the two ‘traditional’ POPs, levonorgestrel (LNG) 30 µg and...

Women empowered by new treatment options

Updates

Following the publication of final draught National Institute for Health and Care Excellence (NICE) guidance on 23 September 2022, approximately 1500 people aged 12 years and older with melanoma are...