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Sharon Rees

Associate Professor Therapeutics and Prescribing, London South Bank University

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Drug Breakdown: Fentanyl

Day 1: A synthetic opioid discovered circa 1960 (from phenylpiperidine) #fentanyl is x 50-100 more potent compared to morphine. Originally for anaesthetic i.v use; also now used for moderate-severe...

Drug breakdown: Bempedoic Acid

With the help of Prescribing and Therapeutics Training Ltd and the Journal of Prescribing Practice, you can earn your 1-hour CPD certificate.

Drug Breakdown: Isotretinoin

Day 1: A synthetic vitamin A derivative, #isotretinoin was discovered in the 1950s & originally used for skin cancer. Its effect on the cell cycle led to the discovery of efficacy for severe acne...

Drug Breakdown: Methylphenidate

Day 1: The mild CNS stimulant #methylphenidate was synthesised in the1940s & marketed as Ritalin by the 1950s, after recognition it improved concentration. Trialled for many conditions e.g chronic...

Drug Breakdown: Fosfomycin

Day 1: Originally derived from streptomyces bacteria (1960s), the main use for the synthetic oral form of #fosfomycin since the 1990s is for uncomplicated UTIs. Still available i.v for osteomyelitis,...

Drug Breakdown: Minoxidil

Day 1: A vasodilator derived from diallylmelamine in 1960s was found to have a BP lowering effect & #minoxidil was licensed 1970s. Long-term use revealed side-effect of hypertrichosis & trials for...

Drug Breakdown: Infliximab

Day 1: Monoclonal Antibody Drugs (MABs) were first generated in the 1970s and were first licensed in the 1980s for transplant rejection. The advancing technology in the 1990s led to improved B cell...

Book Review

This will be a useful and highly relevant resource for independent prescribers, whether they are clinicians considering a refresher or students/newly qualified NMPs who need a reference text. The...

Drug Breakdown: Carbimazole

With the help of Prescribing and Therapeutics Training Ltd and the Journal of Prescribing Practice, you can earn your 1-hour CPD certificate .

Drug Breakdown: Sitagliptin

Day 1: In the 1990s, growing insight into incretin roles in type 2 (T2DM) diabetes led to an interest in the breakdown of gut hormone GLP-1. DPP-4 was identified as the best peptidase target and a...

Drug Breakdown: Celecoxib

Day 1: The discovery of the COX-2 channel in the early 1990s led to two new NSAIDs designed and licensed with COX-2 selective action. The new drug target implied therapeutic and adverse drug effect...

Daptomycin

Day 1: #daptomycin was discovered in the late 1980s, when Streptomyces roseoporus bacteria was isolated from a Turkish soil sample. Adverse effects led to delays in clinical trials...

Drug Breakdown: sildenafil (Viagra)

With the help of Prescribing and Therapeutics Training Ltd and the Journal of Prescribing Practice, you can earn your 1-hour CPD certificate .

Drug breakdown: Penthrox

With the help of Prescribing and Therapeutics Training Ltd and the Journal of Prescribing Practice, you can earn your 1-hour CPD certificate

Drug Breakdown: Omalizumab

Dr Sharon Rees @reesprescribe.

Why choose Journal of Prescribing Practice?

Journal of Prescribing Practice shares the latest clinical expertise and professional guidance for non-medical prescribers. Our goal is to provide the knowledge to help you prescribe more efficiently and effectively.

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