References

Anand R, DeWilde S, Page C Trounce's Clinical Pharmacology for Nurses and Allied Health Professionals, 19th edn. : Elsevier; 2021

Bakker MH, Hugtenburg JG, van Straten A, van der Horst HE, Slottje P Effectiveness of low-dose amitriptyline and mirtazapine for insomnia disorder: study protocol of a randomised, double-blind, placebo-controlled trial in general practice (the DREAMING study). BMJ Open. 2021; 11:(9) https://doi.org/10.1136/bmjopen-2020-047142

British National Formulary. Amitriptyline hydrochloride. 2024. https://bnf.nice.org.uk/drugs/amitriptyline-hydrochloride/#indications-and-dose (accessed 15 January 2025)

Bryson HM, Wilde MI Amitriptyline. Drugs Aging. 1996; 8:(6)459-476 https://doi.org/10.2165/00002512-199608060-00008

Buchbinder R, van Tulder M, Öberg B, Costa LM, Woolf A, Schoene M, Croft P, Buchbinder R, Hartvigsen J, Cherkin D Low back pain: a call for action. Lancet. 2018; 391:(10137)2384-2388 https://doi.org/10.1016/S0140-6736(18)30488-4

Ford AC, Wright-Hughes A, Alderson SL, Ow PL, Ridd MJ, Foy R, Bianco G, Bishop FL, Chaddock M, Cook H Amitriptyline at Low-Dose and Titrated for Irritable Bowel Syndrome as Second-Line Treatment in primary care (ATLANTIS): a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet. 2023; 402:(10414)1773-1785 https://doi.org/10.1016/S0140-6736(23)01523-4

Foster NE, Anema JR, Cherkin D, Chou R, Cohen SP, Gross DP, Ferreira PH, Fritz JM, Koes BW, Peul W Prevention and treatment of low back pain: evidence, challenges, and promising directions. Lancet. 2018; 391:(10137)2368-2383 https://doi.org/10.1016/S0140-6736(18)30489-6

Hayden J, van Tulder MW, Malmivaara A, Koes BW Exercise therapy for treatment of non-specific low back pain. Cochrane Libr. 2005; 2011:(2) https://doi.org/10.1002/14651858.CD000335.pub2

Hill JC, Dunn KM, Lewis M, Mullis R, Main CJ, Foster NE, Hay EM A primary care back pain screening tool: identifying patient subgroups for initial treatment. Arthritis Care Res. 2008; 59:(5)632-641 https://doi.org/10.1002/art.23563

Hill JC, Whitehurst DGT, Lewis M, Bryan S, Dunn KM, Foster NE, Konstantinou K, Main CJ, Mason E, Somerville S Comparison of stratified primary care management for low back pain with current best practice (STarT Back): a randomised controlled trial. Lancet. 2011; 1560-1571 https://doi.org/10.1016/S0140-6736(11)60937-9

Keele University. STarT Back Screening Tool. https://startback.hfac.keele.ac.uk/wp-content/uploads/2018/11/Keele_STarT_Back9_item.pdf/ (accessed 15 January 2025)

Kreiner DS, Matz P, Bono CM, Cho CH, Easa JE, Ghiselli G, Ghogawala Z, Reitman CA, Resnick DK, Watters WC Guideline summary review: an evidence-based clinical guideline for the diagnosis and treatment of low back pain. Spine J. 2020; 20:(7)998-1024 https://doi.org/10.1016/j.spinee.2020.04.006

Maher C, Underwood M, Buchbinder R Non-specific low back pain. Lancet. 2017; 389:(10070)736-747 https://doi.org/10.1016/S0140-6736(16)30970-9

Moore RA, Derry S, Aldington D, Cole P, Wiffen PJ Amitriptyline for neuropathic pain in adults. Cochrane Database Syst Rev. 2015; 2015:(7) https://doi.org/10.1002/14651858

Moseley GL, Butler DS Fifteen Years of Explaining Pain: The Past, Present, and Future. J Pain. 2015; 16:(9)807-813 https://doi.org/10.1016/j.jpain.2015.05.005

NHS England. First contact physiotherapists. 2022. https://www.england.nhs.uk/gp/expanding-our-workforce/first-contact-physiotherapist (accessed 15 January 2025)

National Institute for Health and Care Excellence. Irritable bowel syndrome in adults: diagnosis and management. 2008. https://www.nice.org.uk/guidance/cg61/chapter/Recommendations (accessed 15 January 2025)

National Institute for Health and Care Excellence. Low back pain in over 16s: assessment and management. 2016. https://www.nice.org.uk/guidance/ng59/chapter/Recommendations (accessed 15 January 2025)

National Institute for Health and Care Excellence. Low back pain and sciatica: evidence reviews for pharmacological management of sciatica. 2020. https://www.nice.org.uk/guidance/ng59/evidence/a-evidence-review-for-pharmacological-management-of-sciatica-pdf-8841554318

Noblet T, Marriott J, Hensman-Crook A, O'Shea S, Friel S, Rushton A Independent prescribing by advanced physiotherapists for patients with low back pain in primary care: A feasibility trial with an embedded qualitative component. PLoS One. 2020; 15:(3) https://doi.org/10.1371/journal.pone.0229792

Onghena P, Van Houdenhove B Antidepressant-induced analgesia in chronic non-malignant pain: a meta-analysis of 39 placebo-controlled studies. Pain. 1992; 49:(2)205-219 https://doi.org/10.1016/0304-3959(92)90144-Z

Rainsford KD Ibuprofen: pharmacology, efficacy and safety. Inflammopharmacology. 2009; 17:(6)275-342 https://doi.org/10.1007/s10787-009-0016-x

Saxon R, Gray M, Oprescu F Extended roles for allied health professionals: an updated systematic review of the evidence. J Multidiscip Healthc. 2014; 479-488 https://doi.org/10.2147/JMDH.S66746

Richardson PH, de C, Williams AC Meta-analysis of antidepressant-induced analgesia in chronic pain: comment. [comment]. Pain. 1993; 52:(2) https://doi.org/10.1016/0304-3959(93)90138-F

Sharma CV, Mehta V Paracetamol: mechanisms and updates. Contin Educ Anaesth Crit Care Pain. 2014; 14:(4)153-158 https://doi.org/10.1093/bjaceaccp/mkt049

Grimmer-Somers K, Grimmer-Somers K, Milanese S, Kumar S, Morris J Extended scope physiotherapy roles for orthopedic outpatients: an update systematic review of the literature. J Multidiscip Healthc. 2012; 5:37-45 https://doi.org/10.2147/JMDH.S28891

Stynes S, Jordan KP, Hill JC, Wynne-Jones G, Cottrell E, Foster NE, Goodwin R, Bishop A Evaluation of the First Contact Physiotherapy (FCP) model of primary care: patient characteristics and outcomes. Physiotherapy. 2021; 113:199-208 https://doi.org/10.1016/j.physio.2021.08.002

Tick H, Nielsen A Academic Consortium for Integrative Medicine & Health Commentary to Health and Human Services (HHS) on Inter-agency Task Force Pain Management Best Practices Draft Report. Glob Adv Health Med. 2019; 8 https://doi.org/10.1177/2164956119857656

Urquhart DM, Wluka AE, Heritier S, Fong C, Wang Y, Cicuttini FM Effect of low-dose amitriptyline on low back pain with a neuropathic component: a post hoc analysis. Spine J. 2021; 21:(6)899-902 https://doi.org/10.1016/j.spinee.2021.01.012

Valat JP, Genevay S, Marty M, Rozenberg S, Koes B Sciatica. Best Pract Res Clin Rheumatol. 2010; 24:(2)241-252 https://doi.org/10.1016/j.berh.2009.11.005

World Health Organization. Traitement de la douleur cancéreuse. 1987. https://iris.who.int/bitstream/handle/10665/43944/9241561009_eng.pdf (accessed 15 January 2025)

World Health Organization. Low Back Pain Fact Sheet. 2023. https://www.who.int/news-room/fact-sheets/detail/low-back-pain (accessed 15 January 2025)

Multimodal management of low back pain with sciatica in primary care

02 February 2025
Volume 7 · Issue 2

Abstract

Physiotherapists in the UK are one example of allied health professionals being imbedded into primary care to address specific workstreams to reduce the burden on GPs. By improving access to see a physiotherapist, patients will have quicker access to expert diagnosis and treatment, helping them to manage their musculoskeletal conditions more effectively and recover faster, so they can return to normal life quickly. Low back pain is a common yet complex condition and it is now recognised that a multimodal approach to treatment is required for favourable outcomes. Independent prescribing enables physiotherapists to cover all the recognised elements of management ensuring a seamless patient journey and preventing delayed treatment. This article details the role of a physiotherapist independent prescriber using a case study of a patient with low back pain with sciatica.

Advanced physiotherapy practitioners (APPs) are increasingly being employed as first contact physiotherapy practitioners (FCPPs) in primary care to provide rapid and direct access to expert assessment and advice for any musculoskeletal (MSK) health complaints.

FCPPs who also hold an independent prescribing qualification can further enhance the patient's journey to treatment. They are equipped with specialist assessment and diagnostic skills developed over many years of clinical practice and, in addition, can offer a considered and evidence-based approach to medicines management in keeping with the pathology being treated. Noblet et al (2020) predict that independent prescribing will be a core skill used by FCPPs, given they have been shown to be both safe and cost-effective in managing MSK disorders in primary care without service users needing to first consult with a GP (Stanhope et al, 2012).

Findings from a recent study of 6800 FCPP appointments in England showed that patients attending MSK FCPP clinics as an alternative to seeing a GP experienced significant benefits. They were more likely to be offered expert advice and guidance, with around 70% receiving advice on self-care or exercise. They were also less likely to be referred to consultant-led services, with up to 21% fewer referrals to hospital orthopaedic services (Stynes et al, 2021).

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